FokI Polymorphism of the Vitamin D Receptor Gene Correlates with Parameters of Bone Mass and Turnover in a Female Population of the Italian Island of Lampedusa
β Scribed by A. Falchetti; C. Sferrazza; C. Cepollaro; A. Gozzini; F. Del Monte; L. Masi; N. Napoli; G. Di Fede; V. Cannone; G. Cusumano; M. C. Pandolfo; G. B. Rini; A. Tanini; M. L. Brandi
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 100 KB
- Volume
- 80
- Category
- Article
- ISSN
- 1432-0827
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Vitamin D receptor (VDR) gene polymorphisms have been reported to account for most of the well established genetic influence on bone mineral density (BMD). However, discordant studies have been published and it is still not clear whether VDR genotypes influence bone mass accretion and/or postmenopau
## Abstract Conflicting results have been reported on the association between restriction fragment length polymorphisms (RFLPs) at the vitamin D receptor (VDR) gene locus (i.e., for __Bsm__I, __Apa__I, and __Taq__I) and bone mineral density (BMD). We analyzed this association in a large populationβ
We examined the association of bone mineral density (BMD) with a polymorphism in the gene encoding the vitamin D receptor (VOR) that causes a change in the predicted protein sequence. The polymorphism results from a C-to-T transition and creates an initiation codon (ATG) three codons proximal to a d