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Focused ultrasound for targeted delivery of siRNA and efficient knockdown of Htt expression

✍ Scribed by Burgess, Alison; Huang, Yuexi; Querbes, William; Sah, Dinah W.; Hynynen, Kullervo

Book ID
119291804
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
522 KB
Volume
163
Category
Article
ISSN
0168-3659

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## Abstract ## Background Ultrasound/microbubble‐mediated gene delivery has the potential to be targeted to tissue deep in the body by directing the ultrasound beam following vector administration. Application of this technology would be minimally invasive and benefit from the widespread clinical