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Focused-Ultrasound Disruption of the Blood-Brain Barrier Using Closely-Timed Short Pulses: Influence of Sonication Parameters and Injection Rate

✍ Scribed by Meaghan A. O’Reilly; Adam C. Waspe; Milan Ganguly; Kullervo Hynynen

Book ID
108296011
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
759 KB
Volume
37
Category
Article
ISSN
0301-5629

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## Abstract ## Purpose: To optimize the timing of contrast‐enhanced magnetic resonance imaging (MRI) that best indicates blood–brain barrier (BBB) disruption induced by focused ultrasound (FUS) along with an ultrasound contrast agent (UCA) and to verify that the contrast‐enhanced spin‐echo MRI seq