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Focal Sites of DNA Repair Synthesis in Human Chromosomes

✍ Scribed by Maria P. Svetlova; Liudmila V. Solovjeva; Nadezhda A. Pleskach; Nikolai V. Tomilin


Book ID
115583592
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
528 KB
Volume
257
Category
Article
ISSN
0006-291X

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Band 1q12 is a breakage prone region commonly involved in chromosome 1 rearrangements found in human cancer. We have investigated whether a lack of DNA repair can account for the observed 1q12 fragility. Ethyl methanesulfonate (EMS)-induced repair sites originating in G0/G1 phase of the cell cycle w