Use of the nuclease inhibitor aurintrica
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Wolfgang Walther; Ulrike Stein; Robert Siegel; Iduna Fichtner; Peter M. Schlag
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Article
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2005
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John Wiley and Sons
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English
⚖ 230 KB
## Abstract ## Background Stability, integrity and retention of the DNA within the targeted tissue is decisive for efficient gene transfer using naked DNA. Pre‐clinical and clinical studies require reproducible transfection rates by preventing rapid degradation of naked DNA in the transduced tissu