Focal Atrophy and Cerebrovascular Disease Increase Dementia Risk among Cognitively Normal Older Adults

Increased brain atrophy rates in cogniti

Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid Aβ1-42

✍ Jonathan M. Schott; Jonathan W. Bartlett; Nick C. Fox; Josephine Barnes; for the 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 234 KB 👁 2 views

Objective: To identify cognitively normal individuals at risk of Alzheimer disease (AD) based on cerebrospinal fluid (CSF) Ab1-42, and to determine rates of cerebral atrophy. Methods: Control subjects from the Alzheimer's Disease Neuroimaging Initiative with CSF and serial magnetic resonance imaging