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Focal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells

✍ Scribed by Glodek, A M; Le, Y; Dykxhoorn, D M; Park, S-Y; Mostoslavsky, G; Mulligan, R; Lieberman, J; Beggs, H E; Honczarenko, M; Silberstein, L E

Book ID: 110058279
Publisher: Nature Publishing Group
Year: 2007
Tongue: English
Weight: 243 KB
Volume: 21
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2404769

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## Abstract The tyrosine kinase Fyn is a member of the Src family kinases which are important in many integrin‐mediated cellular processes including cell adhesion and migration. Fyn has multiple phosphorylation sites which can affect its kinase activity. Among these phosphorylation sites, the serin