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Fluvastatin inhibits up-regulation of tissue factor expression by antiphospholipid antibodies on endothelial cells

✍ Scribed by D. E. Ferrara; R. Swerlick; K. Casper; P.L. Meroni; M.E. Vega-Ostertag; E.N. Harris; S. S. Pierangeli


Book ID
109148524
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
176 KB
Volume
2
Category
Article
ISSN
1538-7933

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## Objective: To assess the ability of anti-proteinase 3 (anti-pr3) classic antineutrophil cytoplasmic antibodies (canca) to stimulate endothelial expression of tissue factor (tf), which is the main initiator of the coagulation cascade that can lead to endothelial injury and thrombosis in patients