Fluorospectroscopic studies of mixtures of distearoylphosphatidylcholine and sulfatides with defined fatty acid compositions

✍ Scribed by P. Viani; G. Cervato; S. Marchesini; B. Cestaro

• Book ID: 103039452
• Publisher: Elsevier Science
• Year: 1986
• Tongue: English
• Weight: 465 KB
• Volume: 39
• Category: Article
• ISSN: 0009-3084
• DOI: 10.1016/0009-3084(86)90098-8

✦ Synopsis

Simple study models characteristic for lamellar organization of distearoylphosphatidylcholine and sulfatide have been prepared for fluorospectroscopic investigations on the influence of these glycolipids on the chemico-physical properties of lecithin bilayers. The motion of 1,6-diphenyl-l,3,5-hexatriene in mixed lecithin-sulfatide bilayers changed with temperature, with the compositional ratio of the two lipids, with the presence of divalent cations such as Ca 2÷ and with the fatty acid composition of sulfatide moiety. Steady-state fluorescence measurements of the average motion of the fluorophore permit evaluation of the gel to liquidcrystalline phase transition in all these membrane models containing different sulfatides.