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Fluorometric Titration of the Mitochondrial ADP/ATP Carrier Protein in Muscle Homogenate with Atractyloside Derivatives

✍ Scribed by Pierre Roux; Agnès Le Saux; Christelle Fiore; Christine Schwimmer; Anne-Christine Dianoux; Véronique Trézéguet; Pierre V. Vignais; Guy J.-M. Lauquin; Gérard Brandolin

Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 108 KB
Volume: 234
Category: Article
ISSN: 0003-2697
DOI: 10.1006/abio.1996.0046

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✍ Francois Boulay; Gérard Brandolin; Guy J.M. Lauquin; Pierre V. Vignais 📂 Article 📅 1983 🏛 Elsevier Science 🌐 English ⚖ 732 KB

The chemical synthesis of fluorescent derivatives of atratiyloside (ATR), an inhibitor of the mitochondrial ADP/ATP carrier protein, is described. These derivatives are the following: 6'-O-dansyl ATR, 6'-Odansyl-aminobutyryl ATR, and 6'-O-naphthoyl ATR. The spectral properties of these analogs were