Fluorometric study of antihistamines
β Scribed by Richard E. Jensen; Ronald T. Pflaum
- Publisher
- John Wiley and Sons
- Year
- 1964
- Tongue
- English
- Weight
- 268 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
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## Abstract The antihistaminic effect of terfenadine was studied in the isolated guinea pig ileum, histamine skin wheals in guinea pigs and monkeys, and i.v. histamineβinduced death in guinea pigs. In the guinea pig ileum, terfenadine, 1 Γ 10^β7^ M, shifted the histamine doseβresponse curve to the