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Fluorolactonization of Norbornenecarboxylic Acids and Their Methyl Esters with F-TEDA-BF4 and XeF2.

✍ Scribed by Lyudmila F. Lourie; Yurii A. Serguchev; Galina V. Shevchenko; Maxim V. Ponomarenko; Alexander N. Chernega; Eduard B. Rusanov; Judith A. K. Howard


Publisher
John Wiley and Sons
Year
2006
Weight
23 KB
Volume
37
Category
Article
ISSN
0931-7597

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## Abstract 4‐(Dicyanomethylene)‐3‐methyl‐1‐phenyl‐2‐pyrazoline‐5‐one (1) readily reacts with α‐amino acids and their esters by Michael addition and subsequent elimination of HCN to the adducts 2a–k. One of these, 2i (obtained from methyl glycinate), adds stereoselectively to __N__‐phenylmaleimide