✦ LIBER ✦

Fluorinated retinoic acids and their analogs. 2. Synthesis and biological activity of aromatic 4-fluoro analogs

✍ Scribed by Chan, Ka-Kong; Specian, Anthony C.; Pawson, Beverly A.

Book ID: 125986883
Publisher: American Chemical Society
Year: 1981
Tongue: English
Weight: 556 KB
Volume: 24
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm00133a020

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Fluorinated retinoic acids and their ana

Fluorinated retinoic acids and their analogs. 3. Synthesis and biological activity of aromatic 6-fluoro analogs

✍ Lovey, Allen J.; Pawson, Beverly A. 📂 Article 📅 1982 🏛 American Chemical Society 🌐 English ⚖ 739 KB

Synthesis and biological activity of mer

Synthesis and biological activity of mercaptothiocarboxylic acids and their cyclic analogs

✍ N. I. Lisina; T. P. Vasil'eva; V. M. Bystrova; O. V. Kil'disheva; G. A. Chernov 📂 Article 📅 1987 🏛 Springer 🌐 English ⚖ 530 KB

Enkephalin analogs containing 4,4-difluo

Enkephalin analogs containing 4,4-difluoro-2-aminobutyric acid: Synthesis and fluorine effect on the biological activity

✍ Dirk Winkler; Norbert Sewald; Klaus Burger; Nga N. Chung; Peter W. Schiller 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB 👁 1 views

Analogs of Met-enkephalin and [D-Pen 2 , D-Pen 5 ]enkephalin (DPDPE) containing the partially fluorinated amino acid 4,4-difluoro-2-aminobutyric acid (DFAB) in the 2-or 3-position of the peptide sequence were synthesized and their opioid activities and receptor selectivities were determined in vitro

Boron analogs of amino acids. Synthesis

Boron analogs of amino acids. Synthesis and biological activity of boron analogs of betaine

✍ Spielvogel, Bernard F.; Wojnowich, Leonard; Das, Mrinal K.; McPhail, Andrew T.; 📂 Article 📅 1976 🏛 American Chemical Society 🌐 English ⚖ 299 KB

.alpha.-Methylated analogs of triiodothy

.alpha.-Methylated analogs of triiodothyroalkanoic acids: synthesis and biological activity

✍ Zenker, N.; Ekpe, A. E.; Hubbard, L. S. 📂 Article 📅 1992 🏛 American Chemical Society 🌐 English ⚖ 708 KB

Synthesis and anti-HIV activity of 2′-de

Synthesis and anti-HIV activity of 2′-deoxy-2′-fluoro-4′-C-ethynyl nucleoside analogs

✍ Qiang Wang; Yanfeng Li; Chuanjun Song; Keduo Qian; Chin-Ho Chen; Kuo-Hsiung Lee; 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 271 KB

Based on the favorable antiviral profiles of 4'-substituted nucleosides, novel 1-(2'-deoxy-2'-fluoro-4'-C-ethynyl-beta-D-arabinofuranosyl)-uracil (1a), -thymine (1b), and -cytosine (2) analogs were synthesized. Compounds 1b and 2 exhibited potent anti-HIV-1 activity with IC(50) values of 86 and 1.34