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Fluorimetric micro-determination of kynurenic acid, an endogenous blocker of neurotoxicity, by high-performance liquid chromatography

โœ Scribed by Katsumi Shibata

Book ID
108449473
Publisher
Elsevier Science
Year
1988
Weight
316 KB
Volume
430
Category
Article
ISSN
0378-4347

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An isocratic reverse-phase \(\mathrm{C} 18 \mathrm{high}\)-performance liquid chromatography (HPLC) technique for methylmalonic acid (MMA) with fluorescence detection is described. MMA is extracted from an acidified sample (plasma, urine, etc.) with ethyl acetate. The extract is dried and derivatize