Topical oral cavity pharmacokinetic mode
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Douglas C. Scott; John W. Coggan; Charles A. Cruze; Tao He; Robert D. Johnson
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Article
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2009
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John Wiley and Sons
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English
β 162 KB
A pharmacokinetic model was developed describing the pharmacokinetics of stannous fluoride in human subjects after oral topical application of a stannous fluoride dentifrice. Twenty subjects participated in an investigation of an experimental dentifrice. Subjects rinsed their mouths with the experim