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Fluorescent Probes for Cytochrome P450 Structural Characterization and Inhibitor Screening

✍ Scribed by Dunn, Alexander R.; Hays, Anna-Maria A.; Goodin, David B.; Stout, C. David; Chiu, Richard; Winkler, Jay R.; Gray, Harry B.


Book ID
126111890
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
212 KB
Volume
124
Category
Article
ISSN
0002-7863

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Cytochrome P-450 was detected in microsomes and presumably in cytosol of Neurospora crassa, and was found to be inducible by progesterone. In the microsomal fraction cytochrome b5 and NADPHcytochrome c reductase activities were measurable, too. Cytochrome P-450 of Neurospora crassa is inhibited by S