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Fluorescent peptide probes for in vivo diagnostic imaging

✍ Scribed by Ching-Hsuan Tung

Publisher
Wiley (John Wiley & Sons)
Year
2004
Tongue
English
Weight
310 KB
Volume
76
Category
Article
ISSN
0006-3525

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✦ Synopsis

Abstract

Recently, many novel peptide‐based near‐infrared (NIR) fluorescent molecular probes have been developed for in vivo biomedical imaging. To report specific information of biological targets, the probes were individually designed according to the unique property or functions of their targets. These peptide‐based probes can be classified into targeting, crosslinking, and enzyme‐activatable probes. Several of them have been tested in various in vitro and in vivo models, and the obtained imaging information has been applied to disease detection, medical diagnosis, and drug evaluations. © 2004 Wiley Periodicals, Inc. Biopolymers (Pept Sci), 2004

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