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Fluorescent in-situ hybridization (FISH) as an aid to marker chromosome identification in prenatal diagnosis

✍ Scribed by Amiel, A.; Fejgin, M.; Appelman, Z.; Shapiro, I.; Gaber, E.; Bachar, A.; Zamir, R.; Kedar, I.; Golbus, M.


Book ID
123337073
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
508 KB
Volume
59
Category
Article
ISSN
0301-2115

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A balanced complex chromosome rearrangement (BCCR) involving 3 chromosomes with 4 breakpoints, was identified in a 36-yr-old woman who was studied because her fetus was discovered to have an unbalanced reciprocal translocation (7q;lOq). Analysis of high resolution bands and the application of fluore