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Fluorescent In Situ Hybridization Evaluation of p53 Gene Deletions at a Tumor Interface of Lingual Carcinoma

✍ Scribed by Gregory Hartig; Jianhua Zhang; G. Marta Voytovich; Michael Newton; Alice Chen; Savita P. Collins; Shi-Qi Wu


Book ID
110082422
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
513 KB
Volume
110
Category
Article
ISSN
0023-852X

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## Background: A fluorescence in situ hybridization (fish) technique using specific dna probes allows for the detection of chromosomal aberrations and gene deletions and gains, even in interphase nuclei in human solid tumors. a high frequency of aberrations of chromosome 17 and mutation of the p53