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Fluorescent and photo-affinity enkephalin derivatives: Preparation and interaction with opiate receptors

✍ Scribed by E. Hazum; K-J Chang; Y. Shechter; S. Wilkinson; P. Cuatrecasas

Book ID: 118313658
Publisher: Elsevier Science
Year: 1979
Tongue: English
Weight: 286 KB
Volume: 88
Category: Article
ISSN: 0006-291X
DOI: 10.1016/0006-291x(79)91485-2

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## Abstract The title compound, an analogue of [Leu^5^]‐enkephalin with L‐__o__‐carboranylalanine replacing L‐phenylalanine in position 4, was prepared by fragment condensation. The analogue has a 3‐fold higher affinity for rat brain opiate receptors in the [^3^H]naloxone competition assay than nat