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Fluorescence titration with apoflavodoxin: A sensitive assay for riboflavin 5′-phosphate and flavin adenine dinucleotide in mixtures

✍ Scribed by Johannes H. Wassink; Stephen G. Mayhew


Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
440 KB
Volume
68
Category
Article
ISSN
0003-2697

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✦ Synopsis


A method is described for determining riboflavin 5'-phosphate (FMN) and flavin adenine dinucleotide (FAD) in mixtures by fluorimetric titration with the FMN-specific apoprotein of flavodoxin from Peptostreptococcus elsdenii.

Accurate determinations can be carried out in the presence of a variety of compounds that decrease the fluorescence yield of FMN; the method may therefore be especially useful in the analysis of crude protein-free extracts of biological materials.