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Fluorescence study of substrate binding to carboxypeptidase A

✍ Scribed by Feitelson, Jehuda; Lasser, Nechama

Book ID
127106400
Publisher
American Chemical Society
Year
1971
Tongue
English
Weight
525 KB
Volume
10
Category
Article
ISSN
0006-2960

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✍ K. Zhang; J. Dong; D.S. Auld πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 182 KB

A time-resolved XAFS investigation has been carried out during substrate hydrolysis of Z-Sar-Phe by carboxypeptidase A (ZnCPD), a zinc containing metalloprotease. Time-dependent XAFS spectral changes observed are consistent with the spectral changes from the freeze-trapped enzyme-substrate intermedi