Fluorescence studies on the binding between 1–47 fragment of cholecystokinin receptor CCKA-R(1–47) and nonsulfated cholecystokinin octapeptide CCK8

Receptor fragment approach to the bindin

Receptor fragment approach to the binding between CCK8 peptide and cholecystokinin receptors: A fluorescence study on type B receptor fragment CCKB-R (352–379)

✍ Stefania De Luca; Marina Sanseverino; Ivana Zocchi; Carlo Pedone; Giancarlo More 📂 Article 📅 2005 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 161 KB

## Abstract Fluorescence titrations in a membrane mimetic solvent system allowed us to estimate that the dissociation constant of the bimolecular complex between CCK8 peptide and cholecystokinin type B receptor fragment CCK~B~‐R (352–379) is in the micromolar range. When considered in the context o