Analysis of the structure of HIV-1 prote
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Maciej Geller; Maria Miller; Stanley M. Swanson; Jacob Maizel
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Article
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1997
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John Wiley and Sons
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English
β 130 KB
π 2 views
Six models of the catalytic site of HIV-1 protease complexed with a reduced peptide inhibitor, MVT-101, were investigated. These studies focused on the details of protonation of the active site, its total net charge and hydrogen bonding pattern, which was consistent with both the observed coplanar c