A Fluorescence Polarization Assay for th
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Stephen M.G Knight; Naoki Umezawa; Hee-Seung Lee; Samuel H Gellman; Brian K Kay
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Article
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2002
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Elsevier Science
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English
⚖ 85 KB
Improper function of the tumor suppressor protein p53 is a contributing factor in many human cancers. In normal cells, p53 acts to arrest the cell cycle in response to DNA damage or nucleotide depletion. One mechanism of regulating the amount of p53 in the cell is through the action of the Double Mi