Fluorescence of unmodified oligonucleotides: A tool to probe G-quadruplex DNA structure

Label-Free Fluorescent Probing of G-Quad

Label-Free Fluorescent Probing of G-Quadruplex Formation and Real-Time Monitoring of DNA Folding by a Quaternized Tetraphenylethene Salt with Aggregation-Induced Emission Characteristics

✍ Yuning Hong; Matthias Häuβler; Jacky W. Y. Lam; Zhen Li; King Keung Sin; Yongqia 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 476 KB 👁 2 views

## Abstract Biosensing processes such as molecular beacons require non‐trivial effort to covalently label or mark biomolecules. We report here a label‐free DNA assay system with a simple dye with aggregation‐induced emission (AIE) characteristics as the fluorescent bioprobe. 1,1,2,2‐Tetrakis[4‐(2‐b