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Fluorescence microsatellite analysis to study the parental origin of the supernumerary chromosome in Down's syndrome

✍ Scribed by T.M Ko; H.L Hwa; L.H Tseng; Y.W Lin; Y.P Cheung


Book ID
117128305
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
98 KB
Volume
61
Category
Article
ISSN
0020-7292

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πŸ“œ SIMILAR VOLUMES


Parental origin of the extra chromosome
✍ R. E. Magenis; K. M. Overton; J. Chamberlin; T. Brady; E. Lovrien πŸ“‚ Article πŸ“… 1977 πŸ› Springer 🌐 English βš– 545 KB

Chromosome 21 fluorescent heteromorphisms were studied in 42 patients with Down's syndrome, their parents and their siblings. Included in this number are two instances of an aunt and niece affected with trisomy 21, and one of affected siblings. One case has a de novo 21/21 translocation. Blood group

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✍ U. Langenbeck; I. Hansmann; B. Hinney; V. HΓΆnig πŸ“‚ Article πŸ“… 1976 πŸ› Springer 🌐 English βš– 825 KB

The differential staining methods for chromosomes have led to the demonstration of more chromosomal polymorphisms. Not rarely, these polymorphisms allow in autosomal trisomies the detection of parental origin of the supernumerary chromosome. In addition, the malsegregation may be ascribed to 1st or