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Fluorescence method for the structural analysis of oligomannose-type sugar chains by partial acetolysis

✍ Scribed by Shunji Natsuka; Sumihiro Hase; Tokuji Ikenaka


Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
432 KB
Volume
167
Category
Article
ISSN
0003-2697

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✦ Synopsis


Fluorescence labeling was used in the analysis of partial acetolysis products of oligomannose-type sugar chains with five to nine mannose residues. The principle of the method was the pyridylamination of fragments obtained by the partial acetolysis of pyridylamino sugar chains and the identification of the fragments with an HPLC apparatus equipped with a fluorescence spectrophotometer. The method was tested by analysis of eight oligomannose-type sugar chains with known chemical structures and was found to be effective for analysis of branching structures with samples of 0.5 nmol.