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Fluorescence in situ hybridization for the detection and monitoring of the Ph-positive clone in chronic myelogenous leukemia: comparison with metaphase banding analysis

✍ Scribed by Cuneo, A; Bigoni, R; Emmanuel, B; Smit, E; Rigolin, G M; Roberti, M G; Bardi, A; Piva, N; Scapoli, G; Castoldi, G

Book ID: 110053984
Publisher: Nature Publishing Group
Year: 1998
Tongue: English
Weight: 278 KB
Volume: 12
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2401163

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## Abstract Fluorescence in situ hybridization for the __BCR__/__ABL__ rearrangement in 138 bone marrow specimens from 59 Philadelphia^+^ (Ph^+^) chronic myelogenous leukemia (CML) patients, 35 Ph^+^ acute lymphoblastic leukemia (ALL) patients, and 57 Ph^−^ ALL patients was used. Sixteen (27.1%) of