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Fluorescence in situ hybridization dissection of a chronic myeloid leukemia case bearing the apparently balanced translocations (9;22)(q34;q11.2) and (11;11)(p15;q13)

✍ Scribed by Francesca Malvestiti; Daniela Colombo; Daniele Perego; Ornella Rodeschini; Palma Finelli; Lidia Larizza; Daniela Giardino


Book ID
113513430
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
325 KB
Volume
188
Category
Article
ISSN
0165-4608

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## Abstract Chronic myeloid leukemia (CML) is characterized by the presence of a t(9;22)(q34;q11.2), which leads to the well‐known BCR–ABL1 fusion protein. We describe a patient who was diagnosed clinically with a typical CML but on cytogenetic analysis was found to have a t(9;22)(p24;q11.2). Chrom