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Fluorescence in situ hybridization analyses of hematologic malignancies reveal frequent cytogenetically unrecognized 12p rearrangements

✍ Scribed by Andreasson, P; Johansson, B; Billström, R; Garwicz, S; Mitelman, F; Höglund, M

Book ID: 110053758
Publisher: Nature Publishing Group
Year: 1998
Tongue: English
Weight: 947 KB
Volume: 12
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2400929

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Cytogenetic investigation of nine pancreatic carcinomas revealed structural rearrangements of chromosome 19 in eight cases, resulting in a high frequency of 19p losses and 19q gains. To characterize these imbalances further, we performed fluorescence in situ hybridization (FISH) analysis with 12 map