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Fluorescence Detection of Mexiletine and Its P-Hydroxylated and Hydroxy-Methylated Metabolites in Human Plasma and Urine by High-Performance Liquid Chromatography Using Post-Column Derivatization with O-Phthalaldehyde

โœ Scribed by Tateishi, T.; Harada, K.; Ebihara, A.


Book ID
115503610
Publisher
Informa UK (Taylor & Francis)
Year
1994
Tongue
English
Weight
380 KB
Volume
17
Category
Article
ISSN
0148-3919

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High performance liquid chromatographic
โœ Stanley Lam ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 270 KB ๐Ÿ‘ 1 views

## Abstract A simple, reliable and highly sensitive procedure was devised for measuring the levels of Amicar in blood and urine. 100 ฮผL of serum or urine sample was added to 10 ฮผL of a 10% w/v zinc sulfate solution and 100 ฮผL of methanol, as previously described (Lam __et al.__, 1980) for the remov