𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Fluorescence, CD, and nmr studies on spantide, a bombesin and substance P antagonist

✍ Scribed by Carlo Di Bello; Angelo Scatturin; Gabriella D'Auria; Mario Gargiulo; Livio Paolillo; Enrico Trivellone; Roberto De Castiglione

Publisher
Wiley (John Wiley & Sons)
Year
1991
Tongue
English
Weight
561 KB
Volume
31
Category
Article
ISSN
0006-3525

No coin nor oath required. For personal study only.

✦ Synopsis

The conformational properties of spantide [ (D-Arg', D-Trp7.', Leu") substance PI have been studied by fluorescence, CD, and nmr techniques. The fluorescence, CD, and nmr parameters in different solvents and in a micellar environment (SDS) are compared with the data collected for bombesin. A preliminary investigation on [ D-pro') spantide is also reported.

πŸ“œ SIMILAR VOLUMES

Conformation of bombesin in buffer and i
Conformation of bombesin in buffer and in the presence of lysolecithin micelles: Nmr, CD, and fluorescence studies
✍ P. Cavatorta; A. Spisni; A. G. Szabo; G. Farruggia; L. Franzoni; L. Masotti πŸ“‚ Article πŸ“… 1989 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 879 KB

a m , 431 00 P a m , Italy ## Synopsis The conformation of the tetradecapeptide hormone bornbesin has been studied in buffer and in the presence of lysolecithin mides, using static and dynamic fluorescence, CD, and one and two-dimensional nmr. The reaults obtained show that in buffer bornbesin is

Conformational studies on bombesin antag
Conformational studies on bombesin antagonists: CD and NMR characterization of [Thr6, Leu13ψ(CH2NH) Met14] bombesin (6–14)
✍ Carlo Di Bello; Angelo Scatturin; Gianni Vertuani; Gabriella D'Auria; Mario Garg πŸ“‚ Article πŸ“… 1991 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 738 KB

## Abstract The conformational flexibility of the [Thr^6^, Leu^13^ψ(CH~2~NH) Met^14^]bombesin (6‐14) nonapeptide has been studied by CD and one‐ and two‐dimensional (1D and 2D) nmr techniques. The CD and nmr parameters in different solvents and in a micellar environment (SDS) are compared with the

CD, 1H NMR and molecular modeling studie
CD, 1H NMR and molecular modeling studies of the interaction of Ca2+ with substance P and Ala7-substance P in a non-polar solvent
✍ Xiao-Fei Qi; Boris S. Zhorov; Vettai S. Ananthanarayanan πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 948 KB

The biologically relevant conformation of substance P is likely to be dictated by the lipid milieu wherein the hormone would interact with its receptor. Assuming that specific constraints to the hormone structure may be imparted by its interaction with Ca 2 + ions in the low dielectric lipid medium,