Memory sites toward clinically relevant creatinine have been imparted in polymers based on methacrylic acid, N-vinyl pyrrolidine, and 2-hydroxy ethyl methacrylate by the technique of molecular imprinting. The polymers are subjected to interaction with creatinine and creatine, a molecule of close res
Fluorescence anisotropy studies of molecularly imprinted polymers
β Scribed by Yin-Chu Chen; Zheming Wang; Mingdi Yan; Scott A. Prahl
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 385 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1522-7235
- DOI
- 10.1002/bio.874
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Efforts to elucidate the mechanisms underlying the formation of binding sites in molecularly imprinted polymers (MIPs) and of MIP-ligand binding events are presented in the context of a thermodynamic treatment of MIP recognition phenomena.
Schematic representation of molecular imprinting of the transition state analogue 2 in the polymer matrix.