Fluidised-bed jet milling of pharmaceutical powders
β Scribed by A.C Bentham; C.C Kwan; R Boerefijn; M Ghadiri
- Book ID
- 113860852
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 366 KB
- Volume
- 141
- Category
- Article
- ISSN
- 0032-5910
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Milling is a common procedure to improve bioavailability of many active pharmaceutical ingredients (APIs), which typically have low solubility in water. But such micronization can yield an increase in the cohesiveness of particles. Although particle cohesiveness is desirable for tablet strength in t