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Fluid shear stress enhances the sphingosine 1-phosphate responses in cell–cell interactions between platelets and endothelial cells

✍ Scribed by Shinya Aoki; Makoto Osada; Makoto Kaneko; Yukio Ozaki; Yutaka Yatomi


Book ID
116294992
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
177 KB
Volume
358
Category
Article
ISSN
0006-291X

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The c-fos protein belongs to a family of transcriptional cofactors that can complex with proteins of the Jun family and activate mRNA transcription from gene promoters containing an activator protein 1 (AP-1) binding element. The shear stress inducibility of the c-fos protein was studied in human an