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Fludarabine-induced immunosuppression is associated with inhibition of STAT1 signaling

✍ Scribed by Frank, David A.; Mahajan, Sudipta; Ritz, Jerome

Book ID
109827980
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
247 KB
Volume
5
Category
Article
ISSN
1078-8956

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## Abstract The myeloma cell line RPMI 8226/S and its doxorubicin resistant subline 8226/Dox40 were used as models to explore the potential importance of the STAT1 signaling pathway in drug and radiation resistance. The 40‐fold doxorubicin resistant subline 8226/Dox40 was found to be crossresistant