Fludarabine in the treatment of refractory lymphocytic leukemia (CLL) and low grade lymphoma (LGL)
β Scribed by Gillis, S.; Dann, E.J.; Rachmilewitz, E.A.; Polliack, A.
- Book ID
- 123320919
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 130 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0959-8049
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## Background: The objectives of the study were to evaluate the antileukemic efficacy and toxicity profiles of the combination of fludarabine and intermediate-dose cytosine arabinoside (ara-c) in refractory or relapsed adult acute lymphocytic leukemia (all). patients and methods. thirty adults with
## Purpose The phase II CLL2H trial evaluated safety and efficacy of subcutaneous alemtuzumab in patients with fludarabine-refractory chronic lymphocytic leukemia (CLL). Clinical and biologic markers were evaluated for their impacts on outcome. ## Patients and Methods One hundred nine patients