## Abstract ## BACKGROUND A prospective, singleβarm, openβlabel, nonrandomized Phase 2 study of combined fludarabine and mitoxantrone (FM) plus radioimmunotherapy was conducted to evaluate efficacy and safety in patients with untreated, indolent, nonfollicular nonβHodgkin lymphoma (NHL). ## METHO
Fludarabine and mitoxantrone followed by yttrium-90 ibritumomab tiuxetan in previously untreated patients with follicular non-Hodgkin lymphoma trial: a phase II non-randomised trial (FLUMIZ)
β Scribed by Pier Luigi Zinzani; Monica Tani; Alessandro Pulsoni; Marco Gobbi; Alessio Perotti; Stefano De Luca; Alberto Fabbri; Alfonso Zaccaria; Maria Teresa Voso; Pierpaolo Fattori; Luciano Guardigni; Sonia Ronconi; Maria Giuseppina Cabras; Luigi Rigacci; Amalia De Renzo; Enrica Marchi; Vittorio Stefoni; Mariapaola Fina; Cinzia Pellegrini; Gerardo Musuraca; Enrico Derenzini; Stefano Pileri; Stefano Fanti; Pier Paolo Piccaluga; Michele Baccarani
- Book ID
- 117784631
- Publisher
- The Lancet
- Year
- 2008
- Tongue
- English
- Weight
- 119 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1470-2045
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Background. The epidophyllotoxin VM 26 has been shown to have single-agent activity in patients with diffuse aggressive lymphoma. In an attempt to determine its activity in combination with other agents known to be effective in lymphoma, a Phase I1 trial of a novel chemotherapy regimen was conducted