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FLT3 inhibitors for acute myeloid leukemia: a review of their efficacy and mechanisms of resistance

✍ Scribed by Grunwald, Michael R.; Levis, Mark J.

Book ID
120309444
Publisher
Carden Jennings Publishing
Year
2013
Tongue
English
Weight
520 KB
Volume
97
Category
Article
ISSN
0925-5710

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## Abstract FMS‐like tyrosine kinase 3 (FLT3) is an independent poor prognostic marker of acute myeloid leukemia (AML), and strategies that specifically target FLT3 are therefore of substantial interest. However, previous studies with FLT3 inhibitors as single agents in patients with AML showed few