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Floxed allele for conditional inactivation of the voltage-gated sodium channel β1 subunit Scn1b

✍ Scribed by Chunling Chen; Travis L. Dickendesher; Fumitaka Oyama; Haruko Miyazaki; Nobuyuki Nukina; Lori L. Isom


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
288 KB
Volume
45
Category
Article
ISSN
1526-954X

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Floxed allele for conditional inactivati
✍ Stephen I. Levin; Miriam H. Meisler 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 229 KB

## Abstract The sodium channel gene __Scn8a__ encodes the channel Na~V~1.6, which is widely distributed in the central and peripheral nervous system. Na~V~1.6 is the major channel at the nodes of Ranvier in myelinated axons. Mutant alleles of mouse __Scn8a__ result in neurological disorders includi