Flow-pressure relationship in perfusion studies of the living primate eye

✍ Scribed by Y. Mahler; M. Admoni; U. Ticho

• Book ID: 104646665
• Publisher: Springer-Verlag
• Year: 1984
• Tongue: English
• Weight: 653 KB
• Volume: 56
• Category: Article
• ISSN: 0012-4486
• DOI: 10.1007/bf00155681

✦ Synopsis

Anterior chamber constant rate perfusion studies were performed in normal living monkey eyes.

On careful inspection, the IOP-flow relation was seen to consist of a three stage curve. In the low range of infusions (0-6 tzl/min) IOP raised linearly. In the middle range (6-12 ~l/min) it remained almost constant and raised, again with high infusion rates (12-25 ~I/min).

Calculating outflow facility from this pressure-flow relationship, it was shown that C value was constant in the low infusion range, increased in the middle range and decreased slowly over the high infusion rate range. A comparison was made with a similar curve derived from flow of fluids through non completely collapsible tubes.

The change of lOP following high infusion rates consisted of a decrease in the steadystate pressures achieved. Comparison with formerly observed close phenomena was made and some thoughts about possible causes were brought.