𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Flow injection chemiluminescence determination of isoniazid using the lucigenin–periodate system

✍ Scribed by Jianxiu Du; Jiuru Lu

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
158 KB
Volume
21
Category
Article
ISSN
1522-7235

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A weak chemiluminescence (CL) signal was observed during the mixing of isoniazid with lucigenin in alkaline aqueous solution. The CL signal was enhanced more than 100 times in the presence of potassium periodate. This CL system was developed for the determination of isoniazid using a flow injection mode. The CL intensity is proportional to the concentration of isoniazid in the range 0.005–1.0 mg/L. The limit of detection is 0.0034 mg/L and the relative standard deviation is 2.0% for 0.2 mg/L isoniazid solution in 11 repeated measurements. The method was applied to the determination of isoniazid in pharmaceutical preparations and satisfactory results were obtained. Copyright © 2005 John Wiley & Sons, Ltd.

📜 SIMILAR VOLUMES

Flow-injection determination of streptom
Flow-injection determination of streptomycin residues in milk using the luminol–periodate–Mn2+ chemiluminescence system
✍ Guo-Hui Wan; Hua Cui; Hai-Song Zheng; Yong-Qiang Pang; Li-Juan Liu; Xiao-Feng Yu 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 357 KB 👁 1 views

## Abstract A novel flow‐injection method with chemiluminescence detection was developed for the determination of streptomycin residues in milk, based on the enhancement by streptomycin of the luminol–potassium periodate–Mn^2+^ chemiluminescence system. The assay allowed analysis of streptomycin re

Flow-injection chemiluminescence determi
Flow-injection chemiluminescence determination of catecholamines based on their enhancing effects on the luminol–potassium periodate system
✍ Hong Yao; Yuan Yuan Sun; Xinhua Lin; Jinghua Cheng; Liying Huang 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB 👁 1 views

## Abstract A rapid and sensitive chemiluminescence (CL) method using flow injection analysis is described for the determination of four catecholamines, dopamine, adrenaline, isoprenaline and noradrenaline, based on their greatly enhancing effects on the CL reaction of luminol–potassium periodate i