✦ LIBER ✦

Flow injection analysis NMR (FIA–NMR): a novel flow NMR technique that complements LC–NMR and direct injection NMR (DI–NMR)

✍ Scribed by Paul A. Keifer

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 153 KB
Volume: 41
Category: Article
ISSN: 0749-1581
DOI: 10.1002/mrc.1206

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Details of a new flow NMR technique, flow injection analysis NMR (FIA–NMR), are presented for the first time. This method blends some aspects of both liquid chromatography–NMR and direct injection NMR, and complements both. FIA‐NMR is shown to be useful as an analytical technique, especially for repetitive analyses, and may also prove useful in the analysis of combinatorial chemistry libraries. The feasibility of FIA‐NMR is demonstrated by the quantitative analysis of an over‐the‐counter pharmaceutical. Copyright © 2003 John Wiley & Sons, Ltd.

📜 SIMILAR VOLUMES

Small Volume Flow Probe for Automated Di

Small Volume Flow Probe for Automated Direct-Injection NMR Analysis: Design and Performance

✍ Ronald L Haner; William Llanos; Luciano Mueller 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 145 KB

A detailed characterization of an NMR flow probe for use in direct-injection sample analysis is presented. A 600-MHz, indirect detection NMR flow probe with a 120-microl active volume is evaluated in two configurations: first as a stand-alone small volume probe for the analysis of static, nonflowing

Multicompartment analysis of blood flow

Multicompartment analysis of blood flow and tissue perfusion employing D2O as a freely diffusible tracer: A novel deuterium NMR technique demonstrated via application with murine RIF-1 tumors

✍ Seong-Gi Kim; Joseph J. H. Ackerman 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 965 KB

Deuterium NMR is employed in concert with multicompartment kinetic analysis for measurement of tissue blood flow and perfusion through a bolus administration of D2O as a freely diffusible tracer. The traditional single-compartment and two-compartment in-parallel flow models with no tracer recirculat