## Abstract ## Background: Methods facilitating research in malaria are of pivotal relevance. Flow cytometry offers the possibility of rapid enumeration of parasitemia. It relies on staining the parasite DNA to distinguish between infected and nonβinfected red blood cell (RBC) populations. Unfortu
Flow cytometric enumeration of colonies for in vitro chemotherapeutic drug evaluation
β Scribed by Dr. Jerry T. Thornthwaite; Kathy Loutzenhiser; Francis J. Hornicek; Roger Donahue; Larry M. Allen
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 492 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0196-4763
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An adaptation of a previously reported flow cytometric technique is described. This technique was applied to study the DNA distribution of mouse granulocyte-macrophage colony forming cells (GM-CFc) grown in a methyl cellulose culture system. This method involved the collection of cell clusters and c
Measurement of the frequency of micronuclei induced in cells by ionizing radiation or by chemical treatment is widely used to analyze cytogenetic damage. The microscopic scoring of micronuclei is a tedious and time-consuming procedure. Therefore, attempts have been made to automate micronuclei scori