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Flow cytometric DNA ploidy in colorectal adenomas and family history of colorectal cancer

โœ Scribed by Stefania Sciallero; Hugo Aste; Silvia Bruno; Angela Di Vinci; Elio Geido; Walter Giaretti


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
535 KB
Volume
61
Category
Article
ISSN
0008-543X

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## Abstract A family history of colorectal cancer may increase colorectal cancer risk by influencing adenoma growth or enhancing the formation of new lesions. Data of men from the prospective Health Professionals Followโ€Up Study who underwent an endoscopy between 1986 and 2004 were used to evaluate

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We investigated and compared the DNA content between primary and metastatic lesions from 30 colorectal cancer cases. The findings were only diploid in 2 cases (6.7%) and only aneuploid in 18 cases (60.0%). On the whole, the DNA ploidy agreed in 20 cases (66.7%) between both lesions. In the 18 cases