Flow cytometric DNA ploidy in colorectal adenomas and family history of colorectal cancer
โ Scribed by Stefania Sciallero; Hugo Aste; Silvia Bruno; Angela Di Vinci; Elio Geido; Walter Giaretti
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 535 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0008-543X
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## Abstract A family history of colorectal cancer may increase colorectal cancer risk by influencing adenoma growth or enhancing the formation of new lesions. Data of men from the prospective Health Professionals FollowโUp Study who underwent an endoscopy between 1986 and 2004 were used to evaluate
We investigated and compared the DNA content between primary and metastatic lesions from 30 colorectal cancer cases. The findings were only diploid in 2 cases (6.7%) and only aneuploid in 18 cases (60.0%). On the whole, the DNA ploidy agreed in 20 cases (66.7%) between both lesions. In the 18 cases