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Flow cytometric detection of activation-induced cell death (apoptosis) in peripheral blood lymphocyte subpopulations from healthy cats

✍ Scribed by Edgar Holznagel; Regina Hofmann-Lehmann; Karin Allenspach; Silke Hüttner; Brian Willett; Peter Groscurth; Eva Niederer; Hans Lutz


Book ID
116102789
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
951 KB
Volume
52
Category
Article
ISSN
0165-2427

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Background: Human peripheral blood lymphocytes kept in culture after isolation die by an apoptotic process. Detection of apoptosis with labeled Annexin V to demonstrate loss of plasma membrane asymmetry is sensitive, specific, and easy using flow cytometry. This is true in lymphoblastic cell lines w