Flow cytometric analysis of protein thiol groups in relation to the cell cycle and the intracellular content of glutathione in rat hepatocytes

Bivariate flow cytometric analysis of DN

Bivariate flow cytometric analysis of DNA content versus immunopositivity for ribonucleotide reductase M1 subunit in the cell cycle

✍ Rosanna Mangiarotti; Maria Grazia Bottone; Marco Danova; Carlo Pellicciari 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 250 KB 👁 2 views

Ribonucleotide reductase (RR) is a cytoplasmatic enzyme catalyzing the reduction of all four ribonucleotides to their corresponding deoxyribonucleotides. Its activity strongly correlates to the rate of DNA synthesis. By using a specific monoclonal antibody against the large M1 subunit of RR, we asse