Flow and diffusion of particles in a channel with one porous wall: Polarization chromatography

✍ Scribed by Jocelyne Granger; John Dodds; Dominique Leclerc; Noël Midoux

• Publisher: Elsevier Science
• Year: 1986
• Tongue: English
• Weight: 796 KB
• Volume: 41
• Category: Article
• ISSN: 0009-2509
• DOI: 10.1016/0009-2509(86)85049-7

✦ Synopsis

An analysis is made of the behaviour of a suspension of particles in flow in a rectangular channel with one porous wall, which is the configuration used in a technique for particle chromatography and for cross-flow filtration. General expressions are established for the axial and transversal velocity profiles which reduce to previously published simplified relationships when the channel is short and the membrane permeability is low. An asymptotic solution is given for the diffusion convection equation in this system. Experimental results for the chromatographic separation of latex particles and dextran macromolecules show that the diffusion regime is attained at low flow rates. At higher flow rates the experimental results correspond to a convection regime and at intermediate flow rates we obtain a double peak responses corresponding to both regimes.