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FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)

✍ Scribed by Medema, J. P.


Book ID
111744769
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
444 KB
Volume
16
Category
Article
ISSN
0261-4189

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Here we investigated CD95-mediated JNK activation pathways and their physiological relevance by employing a variety of cell lines with deficiencies in individual signal transmitting proteins. JNK activation was completely dependent on the activation of caspases in type I and type II cells, as reveal